Metabolic disorders, characterized by dysregulated glucose and lipid metabolism, are often associated with chronic inflammation, leading to a range of serious health complications. Conventional treatments for metabolic disorders primarily focus on symptom management and may carry adverse side effects. In recent years, there has been growing interest in exploring natural remedies with anti-inflammatory properties as adjunctive or alternative therapies for metabolic disorders. This review examines the potential of natural remedies for managing metabolic disorders caused by inflammation. We comprehensively summarize the scientific evidence supporting the efficacy of various natural compounds, including polyphenols, omega-3 fatty acids, curcumin, and resveratrol, in modulating inflammatory pathways and improving metabolic parameters. Furthermore, we discuss the mechanisms of action underlying the anti-inflammatory effects of these natural remedies, including their interactions with inflammatory mediators and signaling pathways. Moreover, we explore the clinical implications of incorporating natural remedies into the management of metabolic disorders, including their safety profile, tolerability, and potential synergistic effects with conventional therapies. Challenges and limitations associated with the use of natural remedies, such as variability in bioavailability and standardization, are also addressed. Overall, this review provides valuable insights into the therapeutic potential of natural remedies for alleviating metabolic disorders associated with inflammation. By elucidating the mechanisms of action and clinical evidence supporting their use, we aim to facilitate informed decision-making by healthcare providers and empower individuals with metabolic disorders to adopt evidence-based lifestyle interventions for improved health outcomes.
