Chronic limbic encephalitis can be a major source of morbidity in patients with T1DM. The aim of the case report is to highlight the significance of early identification of signs of memory impairment in patients with T1DM, screening for GAD65 antibodies in the CSF and to be aware of the possible association between limbic encephalitis, GAD65 antibodies and type 1 DM. Limbic Encephalitis (LE) is an inflammatory condition affecting the brain's limbic system, which includes regions critical for memory and emotion.