Erythrokeratoderma is a category of unusual hereditary skin conditions characterized by reddened, dried and thickened skin plaques. Two characteristic forms of lesions exist in erythrokeratoderma: Erythematous transient patches and Hyperkeratotic stable plaques. No clear therapies or recommendations for Erythrokeratoderma are available. Males and women are affected in similar numbers by Erythrokeratoderma. The occurrence in the general populace of the disease is uncertain. The oral retinoids acitretin, etretinate, and isotretinoin were shown to be very effective. When therapy is discontinued, lesions reappear. Prognosis and regular follow-up can be recommended for patients.
