Priya R, Aruna V, Amruthavalli GV, Soundharya R and Gayathri R
Usefulness in the blocking of the glucose assimilation pathway of Candida albicans for developing anti-diabetic drug that might potentially down regulate glucose absorption at intestine is explored in the present paper. Colony characteristics and the microscopic distinctions of the organism grown in yeast extract with and without glucose were studied initially. The study findings were then reconciled with the proven efficacy of a herbal preparation and a known drug- Miglitol and thus arrived the above method to be reliable, rapid, reproducible and cost effective for preliminary screening of anti-diabetic drugs. The findings are presented in the paper.
