In broad senses, vitamins are two types- natural and artificial. Based on mode of action on various organs of human body, we found lots of vitamins. Among them, vitamin A, B complex, D, and vitamin E are commonly used artificially. In old ages, and emergency basis, there is no alternative of taking supplementary vitamins. Twenty-eight published articles were carried out for reviewing this composition as a whole. In this modern era, all types of synthetic vitamins are commercially available in markets but experts always suggest ensuring natural, ideal, and balanced diet for proper fitness. Only overdose of synthetic vitamins could make adverse serious effects in human body.